The Institute of Zoology, Chinese Academy of Sciences, has successfully developed a 3D uterus simulation chip, which for the first time, fully replicates the process of human embryo implantation in the laboratory.

Reporters learned from the Institute of Zoology, Chinese Academy of Sciences that researchers Le Qian and Wang Hongmei, in collaboration with domestic and foreign scientific research teams, have successfully developed a 3D embryo implantation model based on microfluidic chips, which for the first time in the laboratory replicates the process of human embryo implantation. The related results were published in the international academic journal "Cell" on December 23. The research indicates that about 10% of patients in China receiving assisted reproductive technology treatment are unable to achieve clinical pregnancy after undergoing three or more embryo transfers, leading to a cycle of repeated implantation failures, which is a major challenge faced in the field of assisted reproduction. The development of this technology helps to clarify the core causes of repeated implantation failures, select personalized effective drugs, and simplify the testing process.